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Once opened, the bottle should be kept refrigerated for a maximum of 1 month
doi: 10.1016/S0015-0282(97)00343-9.[PubMed] [CrossRef] [Google Scholar] World Health Organization
This translates to a monthly cost ranging from roughly 14,000 (USD 162.9) (for the lowest dose) to potentially 17,500 (USD 203.6) or more as doses increase
Some researchers choose even longer intervals, spending 6 to 8 weeks at each dose level, particularly if they notice heart rate increases above 10 beats per minute from baseline
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